Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae

Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae

It has been argued that the limited genetic diversity and reduced allelic heterogeneity observed in isolated founder populations facilitates discovery of loci contributing to both Mendelian and complex disease. A strong founder effect, severe isolation, and substantial inbreeding have dramatically r...

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Main Authors: Lowe, Jennifer K. (Author), Maller, Julian B. (Author), Pe'er, Itsik (Author), Neale, Benjamin M. (Author), Salit, Jacqueline (Author), Kenny, Eimear E. (Author), Shea, Jessica L. (Author), Burkhardt, Ralph (Author), Smith, J. Gustav (Author), Ji, Weizhen (Author), Noel, Martha (Author), Foo, Jia Nee (Author), Blundell, Maude L. (Author), Skilling, Vita (Author), Garcia, Laura (Author), Sullivan, Marcia L. (Author), Lee, Heather E. (Author), Labek, Anna (Author), Ferdowsian, Hope (Author), Auerbach, Steven B. (Author), Lifton, Richard P. (Author), Newton-Cheh, Christopher (Author), Breslow, Jan L. (Author), Stoffel, Markus (Author), Daly, Mark J. (Author), Altshuler, David (Contributor), Friedman, Jeffrey M. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-06-23T15:24:01Z.
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