Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo

Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo

Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or environmental conditions that either suppress or induce HR cause genomic instability. Despite its importance in carcinogenesis, due to limitati...

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Main Authors: Sukup-Jackson, Michelle R. (Contributor), Kiraly, Orsolya (Contributor), Na, Li (Author), Rowland, Elizabeth A. (Contributor), Winther, Kelly E. (Contributor), Chow, Danielle N. (Contributor), Kimoto, Takafumi (Contributor), Matsuguchi, Tetsuya (Contributor), Jonnalagadda, Vidya S. (Contributor), Maklakova, Vilena I. (Author), Singh, Vijay R. (Author), Wadduwage, Dushan N. (Author), Rajapakse, Jagath (Author), So, Peter T. C. (Contributor), Collier, Lara S. (Author), Engelward, Bevin P. (Contributor), Kay, Jennifer Elizabeth (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-06-30T13:17:36Z.
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