The benefits of selecting phenotype-specific variants for applications of mixed models in genomics

Applications of linear mixed models (LMMs) to problems in genomics include phenotype prediction, correction for confounding in genome-wide association studies, estimation of narrow sense heritability, and testing sets of variants (e.g., rare variants) for association. In each of these applications,...

Full description

Bibliographic Details
Main Authors: Lippert, Christoph (Author), Quon, Gerald (Contributor), Kang, Eun Yong (Author), Kadie, Carl M. (Author), Listgarten, Jennifer (Author), Heckerman, David (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-07-09T15:46:36Z.
Subjects:
Online Access:Get fulltext