Characterizing deformability and surface friction of cancer cells

Metastasis requires the penetration of cancer cells through tight spaces, which is mediated by the physical properties of the cells as well as their interactions with the confined environment. Various microfluidic approaches have been devised to mimic traversal in vitro by measuring the time require...

Full description

Bibliographic Details
Main Authors: Byun, Sangwon (Contributor), Son, Sungmin (Contributor), Amodei, Dario (Author), Cermak, Nathan (Contributor), Shaw, Josephine (Contributor), Kang, Joon Ho (Contributor), Hecht, Vivian Chaya (Contributor), Mallick, Parag (Author), Winslow, Monte Meier (Author), Jacks, Tyler E (Author), Manalis, Scott R (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Winslow, Monte M. (Contributor), Jacks, Tyler E. (Contributor), Manalis, Scott R. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-07-10T19:11:13Z.
Subjects:
Online Access:Get fulltext