One-electron Oxidation of a Pyrenyl Photosensitizer Covalently Attached to DNA and Competition Between its Further Oxidation and DNA Hole Injection

The photosensitized hole injection and guanine base damage phenomena have been investigated in the DNA sequence, 5'-d(CATG[subscript 1] [superscript Py]CG[subscript 2]TCCTAC) with a site-specifically positioned pyrene-like (Py) benzo[a]pyrene 7,8-diol 9,10-epoxide-derived N[superscript 2]-guani...

Full description

Bibliographic Details
Main Authors: Yun, Byeong Hwa (Author), Dedon, Peter C. (Contributor), Geacintov, Nicholas E. (Author), Shafirovich, Vladimir (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2014-08-18T18:23:16Z.
Subjects:
Online Access:Get fulltext