The small molecule, genistein, increases hepcidin expression in human hepatocytes

The small molecule, genistein, increases hepcidin expression in human hepatocytes

Hepcidin, a peptide hormone that decreases intestinal iron absorption and macrophage iron release, is a potential drug target for patients with iron overload syndromes because its levels are inappropriately low in these individuals. Endogenous stimulants of Hepcidin transcription include bone morpho...

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Main Authors: Zhen, Aileen W. (Author), Nguyen, Nancy H. (Author), Gibert, Yann (Author), Motola, Shmulik (Contributor), Buckett, Peter (Author), Wessling-Resnick, Marianne (Author), Fraenkel, Ernest (Contributor), Fraenkel, Paula G. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2014-08-19T18:11:24Z.
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