Enhanced ex vivo expansion of adult mesenchymal stem cells by fetal mesenchymal stem cell ECM

Enhanced ex vivo expansion of adult mesenchymal stem cells by fetal mesenchymal stem cell ECM

Large-scale expansion of highly functional adult human mesenchymal stem cells (aMSCs) remains technologically challenging as aMSCs lose self renewal capacity and multipotency during traditional long-term culture and their quality/quantity declines with donor age and disease. Identification of cultur...

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Main Authors: Ng, Chee Ping (Author), Mohamed Sharif, Abdul Rahim (Author), Heath, Daniel E. (Author), Chow, John W. (Author), Zhang, Claire BY (Author), Chan-Park, Mary B. (Author), Hammond, Paula T. (Contributor), Chan, Jerry K. Y. (Author), Griffith, Linda G. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-08-21T18:30:04Z.
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