Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells

Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells

Immunodeficient mouse-human chimeras provide a powerful approach to study host-specific pathogens, such as Plasmodium falciparum that causes human malaria. Supplementation of immunodeficient mice with human RBCs supports infection by human Plasmodium parasites, but these mice lack the human immune s...

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Main Authors: Chen, Qingfeng (Author), Amaladoss, Anburaj (Author), Ye, Weijian (Author), Liu, Min (Author), Dummler, Sara (Author), Kong, Fang (Author), Wong, Lan Hiong (Author), Loo, Hooi Linn (Author), Loh, Eva (Author), Tan, Shu Qi (Author), Tan, Thiam Chye (Author), Chang, Kenneth T. E. (Author), Dao, Ming (Contributor), Suresh, Subra (Author), Preiser, Peter R. (Author), Chen, Jianzhu (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-08-29T14:31:13Z.
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