Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression

Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression

Activity of glycogen synthase kinase-3β (GSK-3β) is required for long-term depression (LTD) via molecular mechanisms that are incompletely understood. Here, we report that PSD-95, a major scaffold protein of the postsynaptic density (PSD) that promotes synaptic strength, is phosphorylated on threoni...

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Bibliographic Details
Main Authors: Nelson, Christopher D. (Contributor), Kim, Myung Jong (Contributor), Hsin, Honor (Contributor), Chen, Yelin (Contributor), Sheng, Morgan (Contributor)
Other Authors: Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Society for Neuroscience, 2014-09-02T15:19:23Z.
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