Simulated Surface-Induced Thrombin Generation in a Flow Field

A computational model of blood coagulation is presented with particular emphasis on the regulatory effects of blood flow, spatial distribution of tissue factor (TF), and the importance of the thrombomodulin-activated protein C inhibitory pathway. We define an effective prothrombotic zone that extend...

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Bibliographic Details
Main Authors: Jordan, S.W (Author), Chaikof, Elliot L. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-09-22T17:22:02Z.
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