Differentiated human stem cells resemble fetal, not adult, β cells

Differentiated human stem cells resemble fetal, not adult, β cells

Human pluripotent stem cells (hPSCs) have the potential to generate any human cell type, and one widely recognized goal is to make pancreatic β cells. To this end, comparisons between differentiated cell types produced in vitro and their in vivo counterparts are essential to validate hPSC-derived ce...

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Bibliographic Details
Main Authors: Hrvatin, Sinisa (Author), O'Donnell, Charles William (Contributor), Deng, Francis (Author), Millman, Jeffrey R. (Author), Pagliuca, Felicia Walton (Author), DiIorio, Philip (Author), Rezania, Alireza (Author), Gifford, David K. (Contributor), Melton, Douglas A. (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-09-24T19:12:56Z.
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