Delivery of Antibody Mimics into Mammalian Cells via Anthrax Toxin Protective Antigen

Antibody mimics have significant scientific and therapeutic utility for the disruption of protein-protein interactions inside cells; however, their delivery to the cell cytosol remains a major challenge. Here we show that protective antigen (PA), a component of anthrax toxin, efficiently transports...

Full description

Bibliographic Details
Main Authors: Liao, Xiaoli (Contributor), Rabideau, Amy E. (Contributor), Pentelute, Bradley L. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: WILEY-VCH Verlag GmbH & Co., 2014-09-25T16:21:42Z.
Subjects:
Online Access:Get fulltext