Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance

Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance

Diet-induced obesity (DIO) predisposes individuals to insulin resistance, and adipose tissue has a major role in the disease. Insulin resistance can be induced in cultured adipocytes by a variety of treatments, but what aspects of the in vivo responses are captured by these models remains unknown. W...

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Bibliographic Details
Main Authors: Lo, Kinyui Alice (Contributor), Labadorf, Adam (Contributor), Kennedy, Norman J (Author), Han, Myoung Sook (Author), Yap, Yoon Sing (Author), Matthews, Bryan (Contributor), Xin, Xiaofeng (Contributor), Sun, Lei (Author), Davis, Roger J (Author), Lodish, Harvey F. (Contributor), Fraenkel, Ernest (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Yap, Yoon Sing (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-10-02T18:58:25Z.
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