Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function

Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function

Filopodia are long plasma membrane extensions involved in the formation of adhesive, contractile, and protrusive actin-based structures in spreading and migrating cells. Whether filopodia formed by different molecular mechanisms equally support these cellular functions is unresolved. We used Enabled...

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Bibliographic Details
Main Authors: Barzik, Melanie (Contributor), McClain, Leslie Marie (Contributor), Gupton, Stephanie L. (Author), Gertler, Frank (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Society for Cell Biology, 2014-10-14T20:34:44Z.
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