Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
The specific activation of Toll-like receptors (TLRs) has potential utility for a variety of therapeutic indications including antiviral immunotherapy and as vaccine adjuvants. TLR7 and TLR 8 may be activated by their native ligands, single-stranded RNA, or by small molecules of the imidazoquinoline...
Main Authors: | , , , , , , , , , , , , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2014-10-21T16:21:16Z.
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Subjects: | |
Online Access: | Get fulltext |