Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

Full description

Bibliographic Details
Main Authors: Alabi, Christopher A. (Contributor), Sahay, Gaurav (Contributor), Anderson, Daniel Griffith (Contributor), Langer, Robert S (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2014-10-21T19:35:54Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items