Lipidoid-Coated Iron Oxide Nanoparticles for Efficient DNA and siRNA delivery

Lipidoid-Coated Iron Oxide Nanoparticles for Efficient DNA and siRNA delivery

The safe, targeted and effective delivery of gene therapeutics remains a significant barrier to their broad clinical application. Here we develop a magnetic nucleic acid delivery system composed of iron oxide nanoparticles and cationic lipid-like materials termed lipidoids. Coated nanoparticles are...

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Bibliographic Details
Main Authors: Jiang, Shan (Contributor), Eltoukhy, Ahmed A. (Contributor), Anderson, Daniel Griffith (Contributor), Love, Kevin T (Author), Langer, Robert S (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Love, Kevin T. (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2014-10-31T17:54:46Z.
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