Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

The capacity to repair different types of DNA damage varies among individuals, making them more or less susceptible to the detrimental health consequences of damage exposures. Current methods for measuring DNA repair capacity (DRC) are relatively labor intensive, often indirect, and usually limited...

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Bibliographic Details
Main Authors: Nagel, Zachary D. (Contributor), Margulies, Carrie Marie (Contributor), Chaim, Isaac Alexander (Contributor), McRee, Siobhan K. (Contributor), Mazzucato, Patrizia (Contributor), Ahmad, Anwaar (Contributor), Abo, Ryan (Contributor), Butty, Vincent (Contributor), Forget, Anthony L. (Contributor), Samson, Leona D. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-11-05T21:01:07Z.
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