Modular 'Click-in-Emulsion' Bone-Targeted Nanogels

A new class of nanogel demonstrates modular biodistribution and affinity for bone. Nanogels, ~70 nm in diameter and synthesized via an astoichiometric click-chemistry in-emulsion method, controllably display residual, free clickable functional groups. Functionalization with a bisphosphonate ligand r...

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Bibliographic Details
Main Authors: Heller, Daniel A. (Contributor), Levi, Yair (Contributor), Wallas, Jasmine (Contributor), Pratt, George W. (Contributor), Jiang, Shan (Contributor), Sahay, Gaurav (Contributor), Schroeder, Josh E. (Author), Chyan, Yieu (Contributor), Zurenko, Christopher (Author), Querbes, William (Author), Manzano, Miguel (Contributor), Kohane, Daniel S. (Author), Anderson, Daniel Griffith (Contributor), Pelet, Jeisa (Author), Doloff, Joshua C (Author), Schroeder, Avraham Dror (Author), Langer, Robert S (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Pelet, Jeisa M. (Contributor), Doloff, Joshua C. (Contributor), Schroeder, Avi (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2014-11-07T13:31:27Z.
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