Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

In mammalian embryonic stem cells, the acquisition of pluripotency is dependent on Nanog, but the in vivo analysis of Nanog has been hampered by its requirement for early mouse development. In an effort to examine the role of Nanog in vivo, we identified a zebrafish Nanog ortholog and found that its...

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Main Authors: Xu, Cong (Author), Fan, Zi Peng (Contributor), Fogley, Rachel (Author), DiBiase, Anthony (Author), Trompouki, Eirini (Author), Unternaehrer, Juli (Author), Xiong, Fengzhu (Author), Torregroza, Ingrid (Author), Evans, Todd (Author), Megason, Sean G (Author), Daley, George Q. (Author), Schier, Alexander F (Author), Young, Richard A (Author), Zon, Leonard I (Author), Muller, Patrick (Author), Young, Richard A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-12T13:17:51Z.
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