AZFc Deletions and Spermatogenic Failure: A Population-Based Survey of 20,000 Y Chromosomes

AZFc Deletions and Spermatogenic Failure: A Population-Based Survey of 20,000 Y Chromosomes

Deletions involving the Y chromosome's AZFc region are the most common known genetic cause of severe spermatogenic failure (SSF). Six recurrent interstitial deletions affecting the region have been reported, but their population genetics are largely unexplored. We assessed the deletions' p...

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Bibliographic Details
Main Authors: Rozen, Steven G (Author), Marszalek, Janet D. (Author), Irenze, Kathryn (Author), Skaletsky, Helen (Author), Brown, Laura G. (Author), Oates, Robert D. (Author), Silber, Sherman J (Author), Ardlie, Kristin (Author), Page, David C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Page, David C. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-12T13:35:10Z.
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