Plasmin Triggers a Switch-Like Decrease in Thrombospondin-Dependent Activation of TGF-β1

Plasmin Triggers a Switch-Like Decrease in Thrombospondin-Dependent Activation of TGF-β1

Transforming growth factor-β1 (TGF-β1) is a potent regulator of extracellular matrix production, wound healing, differentiation, and immune response, and is implicated in the progression of fibrotic diseases and cancer. Extracellular activation of TGF-β1 from its latent form provides spatiotemporal...

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Bibliographic Details
Main Authors: Venkatraman, Lakshmi (Author), Chia, Ser-Mien (Author), Narmada, Balakrishnan Chakrapani (Author), White, Jacob K (Author), Bhowmick, Sourav S. (Author), Tucker-Kellogg, Lisa (Author), Yu, Hanry (Author), Dewey, C. Forbes (Contributor), So, Peter T. C. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), White, Jacob K. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-12T13:39:49Z.
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