A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching

Developmental axon branching dramatically increases synaptic capacity and neuronal surface area. Netrin-1 promotes branching and synaptogenesis, but the mechanism by which Netrin-1 stimulates plasma membrane expansion is unknown. We demonstrate that SNARE-mediated exocytosis is a prerequisite for ax...

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Bibliographic Details
Main Authors: McClain, Leslie Marie (Contributor), Winkle, Cortney C. (Author), Valtschanoff, Juli G. (Author), Park, Charles S. (Author), Maglione, Christopher (Author), Gupton, Stephanie L. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, The, 2014-11-12T14:14:16Z.
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