Grounded: Transcriptional Pausing in Naive mESCs

Growing mouse pluripotent stem cells in defined media with signaling inhibitors establishes a naive ground state different from that of cells grown in serum. Recently in Cell, Marks et al. (2012) reported differences in the transcriptional and epigenomic landscapes of naive and serum-exposed mouse s...

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Bibliographic Details
Main Authors: Guenther, Matthew G. (Author), Young, Richard A (Author), Young, Richard A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-19T13:31:50Z.
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