M13 Virus based detection of bacterial infections in living hosts

M13 Virus based detection of bacterial infections in living hosts

We report a first method for using M13 bacteriophage as a multifunctional scaffold for optically imaging bacterial infections in vivo. We demonstrate that M13 virus conjugated with hundreds of dye molecules (M13-Dye) can target and distinguish pathogenic infections of F- pili expressing and F -negat...

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Bibliographic Details
Main Authors: Ghosh, Debadyuti (Contributor), Bardhan, Neelkanth Manoj (Contributor), Belcher, Angela M (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Belcher, Angela M. (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2014-11-20T17:58:15Z.
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