mTOR Signaling in Growth Control and Disease

mTOR Signaling in Growth Control and Disease

The mechanistic target of rapamycin (mTOR) signaling pathway senses and integrates a variety of environmental cues to regulate organismal growth and homeostasis. The pathway regulates many major cellular processes and is implicated in an increasing number of pathological conditions, including cancer...

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Bibliographic Details
Main Authors: Laplante, Mathieu (Contributor), Sabatini, David M (Author), Sabatini, David (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Sabatini, David M. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-11-24T19:15:02Z.
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