Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis
Translesion synthesis (TLS) by Y-family DNA polymerases alleviates replication stalling at DNA damage. Ring-shaped processivity clamps play a critical but ill-defined role in mediating exchange between Y-family and replicative polymerases during TLS. By reconstituting TLS at the single-molecule leve...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences (U.S.),
2014-12-01T18:00:48Z.
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| Subjects: | |
| Online Access: | Get fulltext |