Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
Retrotransposons constitute a major source of genetic variation, and somatic retrotransposon insertions have been reported in cancer. Here, we applied TranspoSeq, a computational framework that identifies retrotransposon insertions from sequencing data, to whole genomes from 200 tumor/normal pairs a...
Main Authors: | , , , , , |
---|---|
Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory Press,
2014-12-02T17:01:44Z.
|
Subjects: | |
Online Access: | Get fulltext |