Molecular Signatures of Human Induced Pluripotent Stem Cells Highlight Sex Differences and Cancer Genes

Molecular Signatures of Human Induced Pluripotent Stem Cells Highlight Sex Differences and Cancer Genes

Although human induced pluripotent stem cells (hiPSCs) have enormous potential in regenerative medicine, their epigenetic variability suggests that some lines may not be suitable for human therapy. There are currently few benchmarks for assessing quality. Here we show that X-inactivation markers can...

Full description

Bibliographic Details
Main Authors: Anguera, Montserrat C (Author), Sadreyev, Ruslan (Author), Zhang, Zhaoqing (Author), Szanto, Attila (Author), Payer, Bernhard (Author), Sheridan, Steven D (Author), Kwok, Showming (Contributor), Haggarty, Stephen J. (Author), Sur, Mriganka (Contributor), Alvarez, Jason (Author), Gimelbrant, Alexander A. (Author), Mitalipova, Maisam (Author), Kirby, James E (Author), Lee, Jeannie T. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Sheridan, Steven D. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2014-12-02T21:36:26Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items