Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

BMP and Wnt signaling pathways control essential cellular responses through activation of the transcription factors SMAD (BMP) and TCF (Wnt). Here, we show that regeneration of hematopoietic lineages following acute injury depends on the activation of each of these signaling pathways to induce expre...

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Main Authors: Trompouki, Eirini (Author), Bowman, Teresa V (Author), Lawton, Lee N. (Contributor), Fan, Zi Peng (Contributor), Wu, Dai-Chen (Author), DiBiase, Anthony (Author), Martin, Corey S (Author), Cech, Jennifer N. (Author), Sessa, Anna K (Author), Leblanc, Jocelyn L (Author), Li, Pulin (Author), Durand, Ellen M (Author), Mosimann, Christian (Author), Heffner, Garrett C (Author), Daley, George Q. (Author), Paulson, Robert F (Author), Young, Richard A (Author), Zon, Leonard I (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Whitehead Institute for Biomedical Research (Contributor), Young, Richard A. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2014-12-08T17:35:04Z.
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