Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

The epithelial-mesenchymal transition (EMT) has been associated with the acquisition of motility, invasiveness, and self-renewal traits. During both normal development and tumor pathogenesis, this change in cell phenotype is induced by contextual signals that epithelial cells receive from their micr...

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Bibliographic Details
Main Authors: Scheel, Christina (Author), Eaton, Elinor Ng (Author), Chaffer, Christine L. (Author), Reinhardt, Ferenc (Author), Kah, Kong-Jie (Contributor), Bell, George (Author), Guo, Wenjun (Author), Rubin, Jeffrey (Author), Richardson, Andrea L (Author), Weinberg, Robert A (Author), Li, Sophia (Contributor), Weinberg, Robert A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Ludwig Center for Molecular Oncology (Massachusetts Institute of Technology) (Contributor), Weinberg, Robert A. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-12-10T19:33:28Z.
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