A fully genetically encoded protein architecture for optical control of peptide ligand concentration

A fully genetically encoded protein architecture for optical control of peptide ligand concentration

Ion channels are among the most important proteins in biology, regulating the activity of excitable cells and changing in diseases. Ideally it would be possible to actuate endogenous ion channels, in a temporally precise and reversible manner, and without requiring chemical cofactors. Here we presen...

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Bibliographic Details
Main Authors: Schmidt, Daniel (Contributor), Tillberg, Paul W. (Contributor), Chen, Fei (Contributor), Boyden, Edward (Author)
Other Authors: Massachusetts Institute of Technology. Materials Processing Center (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Program in Media Arts and Sciences (Massachusetts Institute of Technology) (Contributor), Boyden, Edward Stuart (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-12-16T20:15:52Z.
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