Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages
Protein quality control requires careful regulation of intracellular proteolysis. For DegP, a periplasmic protease, substrates promote assembly of inactive hexamers into proteolytically active cages with 12, 18, 24, or 30 subunits. Here, we show that sensitive activation and cage assembly require co...
| Main Authors: | , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier,
2014-12-16T21:18:54Z.
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| Subjects: | |
| Online Access: | Get fulltext |