Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts
Recent advances in somatic cell reprogramming have highlighted the plasticity of the somatic epigenome, particularly through demonstrations of direct lineage reprogramming of one somatic cell type to another by defined factors. However, it is not clear to what extent this type of reprogramming is ab...
Main Authors: | Kim, Jongpil (Author), Su, Susan C (Author), Wang, Haoyi (Author), Cheng, Albert W. (Contributor), Cassady, John P. (Contributor), Lodato, Michael Anthony (Contributor), Lengner, Christopher J. (Author), Chung, Chee Yeun (Author), Dawlaty, Meelad M. (Author), Tsai, Li-Huei (Contributor), Jaenisch, Rudolf (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Whitehead Institute for Biomedical Research (Contributor), Su, Susan C. (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2014-12-16T21:36:17Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors
by: Kim, Jongpil, et al.
Published: (2012) -
Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons
by: Seung-ick Oh, et al.
Published: (2014-01-01) -
Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors
by: Han-Seop Kim, et al.
Published: (2014-01-01) -
Transdifferentiation of Mouse Embryonic Fibroblasts into Dopaminergic Neurons Reactivates LINE-1 Repetitive Elements
by: Francesco Della Valle, et al.
Published: (2020-01-01) -
Degeneration of dopaminergic neurons due to metabolic alterations and Parkinson’s disease
by: Juhyun eSong, et al.
Published: (2016-03-01)