Role of tautomerism in RNA biochemistry

Role of tautomerism in RNA biochemistry

Heterocyclic nucleic acid bases and their analogs can adopt multiple tautomeric forms due to the presence of multiple solvent-exchangeable protons. In DNA, spontaneous formation of minor tautomers has been speculated to contribute to mutagenic mispairings during DNA replication, whereas in RNA, mino...

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Bibliographic Details
Main Authors: Singh, Vipender (Contributor), Fedeles, Bogdan I. (Contributor), Essigmann, John M. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2014-12-24T16:09:13Z.
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