Role of tautomerism in RNA biochemistry
Heterocyclic nucleic acid bases and their analogs can adopt multiple tautomeric forms due to the presence of multiple solvent-exchangeable protons. In DNA, spontaneous formation of minor tautomers has been speculated to contribute to mutagenic mispairings during DNA replication, whereas in RNA, mino...
Main Authors: | Singh, Vipender (Contributor), Fedeles, Bogdan I. (Contributor), Essigmann, John M. (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory Press,
2014-12-24T16:09:13Z.
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Subjects: | |
Online Access: | Get fulltext |
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