Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo

Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo

Complexin (Cpx) is a SNARE-binding protein that regulates neurotransmission by clamping spontaneous synaptic vesicle fusion in the absence of Ca[superscript 2+] influx while promoting evoked release in response to an action potential. Previous studies indicated Cpx may cross-link multiple SNARE comp...

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Bibliographic Details
Main Authors: Littleton, J. Troy (Contributor), Kummel, Daniel (Author), Baguley, Stephanie Wood (Author), Coleman, Jeff (Author), Rothman, James E. (Author), Cho, Richard W. (Author), Li, Feng, 1968 O (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Cho, Richard William (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-02-05T18:57:18Z.
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