Yeast Reveal a 'Druggable' Rsp5/Nedd4 Network That Ameliorates α-Synuclein Toxicity in Neurons
α-Synuclein (α-syn) is a small lipid-binding protein implicated in several neurodegenerative diseases, including Parkinson's disease, whose pathobiology is conserved from yeast to man. There are no therapies targeting these underlying cellular pathologies, or indeed those of any major neurodege...
Main Authors: | , , , , , , , , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2015-02-12T19:23:03Z.
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Subjects: | |
Online Access: | Get fulltext |