Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems

Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems

Hepatitis B virus (HBV) chronically infects 400 million people worldwide and is a leading driver of end-stage liver disease and liver cancer. Research into the biology and treatment of HBV requires an in vitro cell-culture system that supports the infection of human hepatocytes, and accurately recap...

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Bibliographic Details
Main Authors: Schwartz, Robert E. (Contributor), Ramanan, Vyas (Contributor), Shlomai, Amir (Author), de Jong, Ype P. (Author), Bhatia, Sangeeta N. (Contributor), Rice, Charles M. (Author), Bhatia, Sangeeta N (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-03-04T16:52:15Z.
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