A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Recently, more than 1000 large intergenic noncoding RNAs (lincRNAs) have been reported. These RNAs are evolutionarily conserved in mammalian genomes and thus presumably function in diverse biological processes. Here, we report the identification of lincRNAs that are regulated by p53. One of these li...

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Main Authors: Huarte, Maite (Author), Guttman, Mitchell (Contributor), Feldser, David M. (Contributor), Garber, Manuel (Author), Koziol, Magdalena J. (Author), Kenzelmann-Broz, Daniela (Author), Khalil, Ahmad M. (Author), Zuk, Or (Author), Amit, Ido (Author), Rabani, Michal (Author), Attardi, Laura D. (Author), Regev, Aviv (Contributor), Rinn, John L. (Author), Lander, Eric Steven (Author), Jacks, Tyler E (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Jacks, Tyler E. (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-03-17T15:03:32Z.
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