Mesenchymal Stem Cell Mechanics from the Attached to the Suspended State

Human mesenchymal stem cells (hMSCs) are therapeutically useful cells that are typically expanded in vitro on stiff substrata before reimplantation. Here we explore MSC mechanical and structural changes via atomic force microscopy and optical stretching during extended passaging, and we demonstrate...

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Bibliographic Details
Main Authors: Maloney, John M. (Contributor), Nikova, Dessy (Contributor), Lautenschläger, Franziska (Author), Clarke, Emer (Author), Langer, Robert (Contributor), Guck, Jochen (Author), Van Vliet, Krystyn J. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-03-17T15:36:40Z.
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