Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

MicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions as translational repressor. We show that miR-125b and miR-132, as well as several other miRNAs, are associated with FMRP...

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Bibliographic Details
Main Authors: Edbauer, Dieter (Contributor), Neilson, Joel R. (Contributor), Foster, Kelly A. (Contributor), Wang, Chi-Fong (Contributor), Seeburg, Daniel P. (Contributor), Batterton, Matthew N. (Contributor), Tada, Tomoko (Contributor), Dolan, Bridget M. (Contributor), Sharp, Phillip A. (Contributor), Sheng, Morgan Hwa-Tze (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Sheng, Morgan (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2015-03-19T17:13:54Z.
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