Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

The large serine/threonine protein kinase mTOR regulates cellular and organismal homeostasis by coordinating anabolic and catabolic processes with nutrient, energy, and oxygen availability and growth factor signaling. Cells and organisms experience a wide variety of insults that perturb the homeosta...

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Bibliographic Details
Main Authors: Sengupta, Shomit (Contributor), Peterson, Timothy Richard (Author), Sabatini, David (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Peterson, Timothy R. (Contributor), Sabatini, David M. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2015-03-20T14:33:33Z.
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