Structural and Functional Analysis of Phosphothreonine-Dependent FHA Domain Interactions

Structural and Functional Analysis of Phosphothreonine-Dependent FHA Domain Interactions

Summary: FHA domains are well established as phospho-dependent binding modules mediating signal transduction in Ser/Thr kinase signaling networks in both eukaryotic and prokaryotic species. Although they are unique in binding exclusively to phosphothreonine, the basis for this discrimination over ph...

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Main Authors: Pennell, Simon (Author), Westcott, Sarah (Author), Ortiz-Lombardía, Miguel (Author), Patel, Dony (Author), Li, Jiejin (Author), Nott, Timothy J. (Author), Mohammed, Duaa (Contributor), Buxton, Roger S. (Author), Verma, Chandra (Author), Smerdon, Stephen J. (Author), Yaffe, Michael B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Yaffe, Michael B. (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2015-03-20T18:16:37Z.
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