Rapid Flow-Based Peptide Synthesis

A flow-based solid-phase peptide synthesis methodology that enables the incorporation of an amino acid residue every 1.8 min under automatic control or every 3 min under manual control is described. This is accomplished by passing a stream of reagent through a heat exchanger into a low volume, low b...

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Bibliographic Details
Main Authors: Heider, Patrick L. (Contributor), Adamo, Andrea (Contributor), Vinogradov, Alexander A. (Contributor), Li, Xiyuan (Contributor), Berger, Tatiana (Contributor), Policarpo, Rocco L. (Contributor), Zhang, Chi (Contributor), Zou, Yekui (Contributor), Liao, Xiaoli (Contributor), Spokoyny, Alexander M. (Contributor), Jensen, Klavs F. (Contributor), Pentelute, Bradley L. (Contributor), Simon, Mark (Contributor), Mong, Surin Khai (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2015-03-25T16:46:53Z.
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