A Mathematical Model of Murine Metabolic Regulation by Leptin: Energy Balance and Defense of a Stable Body Weight

We have developed a physiologically based mathematical model, with parameters derived from published experimental data, to simulate the regulatory effects of the leptin pathway on murine energy homeostasis. Model outcomes are consistent with data reported in the literature and reproduce key characte...

Full description

Bibliographic Details
Main Authors: Tam, Joshua (Contributor), Fukumura, Dai (Author), Jain, Rakesh K. (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2015-03-27T18:28:53Z.
Subjects:
Online Access:Get fulltext