Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice

Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice

"Black" pigment gallstones form in sterile gallbladder bile in the presence of excess bilirubin conjugates ("hyperbilirubinbilia") from ineffective erythropoiesis, hemolysis, or induced enterohepatic cycling (EHC) of unconjugated bilirubin. Impaired gallbladder motility is a less...

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Main Authors: Woods, Stephanie E. (Contributor), Leonard, Monika R. (Author), Hayden, Joshua A. (Contributor), Brophy, Megan Brunjes (Contributor), Bernert, Kara R. (Author), Lavoie, Brigitte (Author), Muthupalani, Sureshkumar (Contributor), Whary, Mark T. (Contributor), Mawe, Gary M. (Author), Nolan, Elizabeth M. (Contributor), Carey, Martin C. (Author), Fox, James G. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: American Physiological Society, 2015-03-30T17:24:01Z.
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