Origins and Impacts of New Mammalian Exons

Origins and Impacts of New Mammalian Exons

Mammalian genes are composed of exons, but the evolutionary origins and functions of new internal exons are poorly understood. Here, we analyzed patterns of exon gain using deep cDNA sequencing data from five mammals and one bird, identifying thousands of species- and lineage-specific exons. Most ne...

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Bibliographic Details
Main Authors: Merkin, Jason Jay (Contributor), Chen, Ping (Author), Alexis, Maria Sarah (Contributor), Hautaniemi, Sampsa (Author), Burge, Christopher B (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Burge, Christopher B. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-03-30T19:07:42Z.
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