Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells
Overexpression of transcription factors has been used to directly reprogram somatic cells into a range of other differentiated cell types, including multipotent neural stem cells (NSCs), that can be used to generate neurons and glia. However, the ability to maintain the NSC state independent of the...
Main Authors: | Cassady, John P. (Contributor), D'Alessio, Ana C. (Author), Sarkar, Sovan (Author), Fan, Zi Peng (Contributor), Ganz, Kibibi (Author), Roessler, Reinhard (Author), Sur, Mriganka (Contributor), Young, Richard A (Author), Jaenisch, Rudolf (Contributor), Dani, Vardhan (Contributor), Young, Richard A. (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-03-31T15:37:32Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells
by: John P. Cassady, et al.
Published: (2014-12-01) -
Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors
by: Buganim, Yosef, et al.
Published: (2014) -
JIP2 haploinsufficiency contributes to neurodevelopmental abnormalities in human pluripotent stem cell-derived neural progenitors and cortical neurons
by: Roessler, Reinhard, et al.
Published: (2020) -
Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells
by: Stefan Semrau, et al.
Published: (2017-10-01) -
Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells
by: Semrau, Stefan, et al.
Published: (2018)