Family-wide analysis of poly(ADP-ribose) polymerase activity

Family-wide analysis of poly(ADP-ribose) polymerase activity

The poly(adenosine diphosphate (ADP)-ribose) polymerase (PARP) protein family generates ​ADP-ribose (​ADPr) modifications onto target proteins using ​NAD[superscript +] as substrate. Based on the composition of three ​NAD[superscript +] coordinating amino acids, the H-Y-E motif, each PARP is predict...

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Bibliographic Details
Main Authors: Vyas, Sejal (Contributor), Matic, Ivan (Author), Uchima, Lilen (Contributor), Rood, Jenny (Contributor), Zaja, Roko (Author), Hay, Ronald T. (Author), Ahel, Ivan (Author), Chang, Paul (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-03-31T16:49:32Z.
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